Most important changes (==DIFFERENCES) in my php.ini file compared to the default php.ini file. As well as other PHP configuration files (pool.d/www.conf and conf/20-mysqli.ini files). Sharing is caring.
Note: I'm also running a Nextcloud instance, which require larger uploads & higher limits. Look for yourself what your optimal settings are for max_execution_time, post_max_size and upload_max_filesize.