Under Yosemite (and El Capitan), the launch launchctl utility changed.
For dnsmasq:
brew install dnsmasqorbrew upgrade dnsmasqsudo cp -fv /usr/local/opt/dnsmasq/*.plist /Library/LaunchDaemons- In
/usr/local/etc/dnsmasq.confadd the lineaddress=/devel/127.0.0.1(do NOT adddevas this is now a top-level TLD) sudo launchctl bootstrap system /Library/LaunchDaemons/homebrew.mxcl.dnsmasq.plistsudo launchctl enable system/homebrew.mxcl.dnsmasqsudo launchctl kickstart -kp system/homebrew.mxcl.dnsmasq